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Mechanism of action and application characteristics of antifungal agents


Time:2024-02-21 16:02

Fungicides, as an auxiliary agent in water-based architectural coatings, provide benefits such as anti-corrosion, mildew prevention, and algae prevention. Preservatives protect the coating from microbial contamination in its wet state, while mildew and algae preventatives protect the coating film from microbial infection; this article focuses on mildew-proofing active substances.

As an additive in water-based architectural coatings, fungicides offer benefits such as anti-corrosion, mildew prevention, and algae control. Preservatives protect the coating from microbial contamination in its wet state, while mildew and algae preventatives protect the coating from microbial infection; this article focuses on mildew-preventative active substances.

 

Mechanism of Action of Dry Film Mildew-Preventative Active Substances

The mildew-preventative active ingredients in coatings can act on the cell wall, cell nucleus, or intracellular organelles of fungal cells, either simultaneously or separately, thereby killing fungal spores or inhibiting fungal reproduction.

 

Structure of Dry Film Mildew-Preventative Active Substances

Commonly used mildew preventatives in water-based architectural coatings can be broadly classified by active ingredient: isothiazolinones, benzimidazoles, iodine propargyl compounds, and pyrithiones.

 

Application Characteristics of Dry Film Mildew-Preventative Active Substances

 

Active Substances

Ecological Hazards

Application Characteristics

Isothiazolinones OIT

Toxic

Highly effective broad-spectrum mildew prevention, high water solubility, unstable at PH>10, no discoloration risk

Isothiazolinones DCOIT

Highly Toxic

Moderate mildew prevention efficiency, ineffective against some fungi, easily hydrolyzed, low water solubility, discoloration risk

Benzimidazoles BCM

Toxic

Highly effective mildew prevention, poor effect on Cladosporium, very stable, very low water solubility, no discoloration risk

Iodine Propargyl Compounds IPBC

Highly Toxic

Highly effective broad-spectrum mildew prevention, high water solubility (270 ppm)

Pyrithiones ZnP

Highly Toxic

Good mildew prevention performance, ineffective against some fungi, mildew prevention activity is greatly affected by the formulation, forms soluble salts at PH>8.5, prone to discoloration in the presence of Fe/Cu

 

 

Currently, commonly used mildew preventatives in water-based architectural coatings include OIT, DCOIT, IPBC, BCM, and Diuron. These mildew-preventative active ingredients are often used individually or in combination.

 

Different mildew preventatives have different bactericidal spectra and characteristics. When selecting a fungicide, consider the product's usage environment and purpose. Based on the characteristics of various mildew-preventative active ingredients, use them in combination to achieve both short-term and long-term protection of the coating, thereby achieving the ideal coating effect

 


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